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Erythrasma (Skin fold infection) (Adapted for Sub-Saharan Africa)

Erythrasma (Skin fold infection)

Introduction

Erythrasma, also called cutaneous erythrasma, is a chronic bacterial skin infection. It is common in sub-Saharan Africa due to the warm, humid climate.

The condition mostly affects:

  • People who are overweight
  • People with diabetes
  • Those who sweat excessively
  • People with weakened immune systems
  • Older adults
  • Individuals living in crowded housing or shared spaces

It is not life-threatening but can be persistent, uncomfortable, and sometimes mistaken for fungal infections like ringworm or athlete’s foot.

Discussion

How Does it Look?

Erythrasma usually appears as:

  • Reddish-brown or pink patches with well-defined edges
  • Slightly scaly, wrinkled, or dry skin
  • Mild itchiness or burning (especially in the groin)
  • Cracks or softening of the skin in between the toes (can look like athlete’s foot)
  • On darker skin, it may appear as lighter patches with darker edges

Common areas affected:

  • Armpits
  • Groin
  • Under the breasts
  • Between the buttocks
  • Belly button
  • Inner thighs
  • In between toes
  • Folds of excess skin (stomach, legs)

It is more common in men (groin involvement) and in women (between the toes).

 

Warning Signs and Symptoms

  • Red, pink, or brown patches of skin
  • Mild itching or burning
  • Scaly or wrinkled skin
  • Macerated (softened) skin between toes
  • Small cracks on the feet
  • Rash that resembles ringworm or fungal infection
  • In many people: no symptoms at all

 

Self-Care and Treatment

Most cases can be treated successfully with good hygiene and topical or oral antibiotics.

At home care:

  • Wash affected areas daily with antibacterial soap
  • Keep skin clean and dry, especially in folds
  • Wear loose, light, cotton clothing to reduce sweating
  • Use baby powder to keep skin folds dry
  • Eat a healthy diet and maintain a healthy weight

Medicines that may be used (prescribed by a healthcare worker):

  • Topical antibiotics: Clindamycin cream, Erythromycin cream, Fusidic acid cream, Mupirocin cream, Whitfield’s ointment
  • Oral antibiotics (for widespread or resistant cases): This should be prescribed by a doctor to limit the growing antibiotic resistance
  • Benzoyl peroxide wash to reduce bacteria
  • Mild steroid or antifungal creams (e.g. hydrocortisone, miconazole) for itching or irritation

 

When to Seek Medical Attention

See a healthcare worker if:

  • You notice reddish-brown patches in moist areas that do not improve with self-care
  • The rash spreads, worsens, or looks like ringworm
  • You have diabetes or a weak immune system and notice new patches
  • You develop fever, pain, or spreading infection
  • The skin blisters, peels, or becomes severely irritated
  • You have severe symptoms like breathing problems, swelling of the mouth or face, or widespread rash

 

Prevention

  • Bath or shower daily, especially in hot weather
  • Keep skin dry and clean, especially folds
  • Wear loose cotton clothing that absorbs sweat
  • Avoid staying in very hot, damp conditions for long periods
  • Manage weight to prevent obesity
  • Control blood sugar if you have diabetes
  • Do not share towels or clothing in crowded settings

 

Key Points

  • Erythrasma is common but often overlooked in sub-Saharan Africa.
  • It is caused by bacteria, not fungi, though it may look like fungal infections.
  • Good hygiene, early treatment, and prevention strategies can help control the disease and reduce recurrence.
References
  1. Hay RJ, Johns NE, Williams HC, et al. The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions. J Invest Dermatol. 2014;134(6):1527-1534.
  2. Grice EA, Segre JA. The skin microbiome. Nat Rev Microbiol. 2011;9(4):244-253.
  3. James WD, Berger TG, Elston DM. Andrews’ Diseases of the Skin: Clinical Dermatology. 13th ed. Elsevier; 2019.
  4. Okeke IN, Peeling RW, Goossens H. Skin Infections in the Tropics. Lancet Infect Dis. 2020;20(8):e156-e165.