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Alzheimer’s disease

Introduction

Alzheimer’s disease is a progressive neurodegenerative disorder that primarily affects memory, cognitive function, and behavior. It is the most common cause of dementia, accounting for approximately 60-80% of dementia cases worldwide. The disease is characterized by the accumulation of amyloid plaques and tau tangles in the brain, leading to neuronal dysfunction and cell death. While the exact cause of Alzheimer’s disease remains unclear, risk factors include age, genetics, and lifestyle influences. Early symptoms often include mild memory loss, but as the disease progresses, individuals may experience severe impairment in communication, reasoning, and daily activities. Currently, there is no cure for Alzheimer’s disease, but ongoing research aims to develop effective treatments and preventive strategies.

Discussion
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Conclusion

Alzheimer’s disease presents a significant challenge in the context of ageing, as it severely impacts cognitive abilities and quality of life. While current treatments focus on managing symptoms, early diagnosis and intervention can help slow disease progression. Continued research into the mechanisms of Alzheimer’s disease, along with lifestyle modifications such as a healthy diet, mental stimulation, and regular physical activity, can play a crucial role in reducing risk factors. As the global population continues to age, it is essential to prioritize resources and policies that support individuals affected by Alzheimer’s disease and their caregivers, ensuring a more inclusive and informed approach to neurodegenerative disorders.

References

Alzheimer’s Association. (2022). “Alzheimer’s Disease Facts and Figures.” Retrieved from https://www.alz.org

Selkoe, D. J., & Hardy, J. (2016). “The amyloid hypothesis of Alzheimer’s disease at 25 years.” EMBO Molecular Medicine, 8(6), 595-608.